BI 7189

CAS No. 1883429-32-0

BI 7189 ( BI7189 )

Catalog No. M12928 CAS No. 1883429-32-0

BI 7189 is a highly selective bromodomains of BRD9 and BRD7 inhibitor with IC50<50 nM for BRD9.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    BI 7189
  • Note
    Research use only, not for human use.
  • Brief Description
    BI 7189 is a highly selective bromodomains of BRD9 and BRD7 inhibitor with IC50<50 nM for BRD9.
  • Description
    BI 7189 is a highly selective bromodomains of BRD9 and BRD7 inhibitor with IC50<50 nM for BRD9, displays >1,000 fold selectivity over the bromodomains of BRD4; suppresses the proliferation of AML cells.
  • Synonyms
    BI7189
  • Pathway
    Chromatin/Epigenetic
  • Target
    Bromodomain
  • Recptor
    Bromodomain
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1883429-32-0
  • Formula Weight
    330.43
  • Molecular Formula
    C19H26N2O3
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    ——
  • Chemical Name
    5-[4-[(dimethylamino)methyl]-3,5-dimethoxyphenyl]-1,3,6-trimethylpyridin-2-one

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Hohmann AF, et al. Nat Chem Biol. 2016 Sep;12(9):672-9.
2. Pérez-Salvia M, et al. Epigenetics. 2017 May 4;12(5):323-339.
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